People with varicose veins are at significant risk of developing a potentially fatal blood clot, research suggests.
A
study of 425,000 people suggests the condition should be considered a
major red flag that someone is at risk of deep vein thrombosis (DVT) or
pulmonary embolism.
Researchers found
people with varicose veins were at a five times increased risk of
developing DVT - a clot in the legs which can lead to amputation or even
death.
And they were twice as likely to develop a pulmonary embolism - a clot which travels into the lungs and can be deadly.They also had double the risk of peripheral arterial disease, which reduces blood flow to the arms and legs.
What are varicose veins?
Varicose veins are swollen and enlarged veins that usually occur on the legs and feet.
They occur when the valves in the veins break down, allowing blood to flow backwards and collect at certain points.
The problem is usually minor, affecting a quarter of people in the UK at some point in their life.
But
the new study, by researchers in Taiwan, suggests it should be
considered a warning sign that someone is at risk of more serious
issues.
Each year about 25,000 people
in the UK die from a blood clot in a vein, and the condition is also the
third leading cause of heart attacks and strokes.
Inflammation thought to be responsible
The
China Medical University team are unsure whether the varicose veins
actually cause blood clots, or whether they are are a symptom of deeper
problems which are a common cause of both varicose veins and the more
serious clotting problems.
But they believe inflammation in the veins are probably involved, whichever the cause.
Writing
in the JAMA medical journal, they said: ‘Patients with varicose veins
have increased levels of inflammatory and pro-thrombotic markers.’
‘Varicose veins are rarely associated with serious health risks.
‘In
contrast DVT, pulmonary embolism and peripheral arterial disease are
vascular diseases that are associated with serious systemic effects.’
They
added: ‘Whether the association between varicose veins and DVT is
causal or represents a common set of risk factors requires further
research.’-(DAILY MAIL HEALTH)
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